多发性Spitz痣一例

患儿,男,5岁。8个月时左侧鼻部出现米粒大褐色丘疹,逐渐增大成为红褐色结节,类似皮疹于左侧面部不断发生,病理检查示：真表皮交界处及真皮内弥散性梭形痣细胞浸润,呈对称分布,痣细胞巢垂直于表皮。免疫组化示：Ki-67（〈2%-3%＋）,HMB45（＋）,S-100（＋）。

Multiple Spitz nevi:a case report

A 5-year-old male presented with a brown grain-like macula on the left side of the nose since 8 months old. The size of the lesion increased gradually and similar rashes appeared on the left face. Biopsy showed scattered spindle-shaped melanocytes in the junction of epidermis and dermis symmetrically and ne-vus cell nests with vertical orientation. Immunohistochemical analysis showed Ki-67 (<2%-3%+) , HMB45 (-) , S-100(+) .