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超敏C-反应蛋白(hs-CRP)检测在儿科细菌感染性疾病中的应用价值
引用本文:杨惠聪,原敏,杨彩娥. 超敏C-反应蛋白(hs-CRP)检测在儿科细菌感染性疾病中的应用价值[J]. 现代诊断与治疗, 2009, 20(5): 268-270
作者姓名:杨惠聪  原敏  杨彩娥
作者单位:1. 福建医科大学附属漳州市医院检验科,福建,漳州,363000
2. 福建医科大学附属漳州市医院输血科,福建,漳州,363000
3. 福建医科大学技术与工程学院,福建,漳州,363000
摘    要:
目的探讨血清中超敏C-反应蛋白(hs-CRP)检测在儿童细菌性感染疾病中的诊断价值。方法(1)用OLYMPUS AU2700全自动生化仪检测148例细菌性感染患儿(观察组)及55例健康儿(对照组)的hs-CRP含量。(2)用拜耳AD-VIA2120全自动血细胞仪对上述148例细菌性感染患儿及55例健康儿进行白细胞计数。(3)将以上两种方法做统计学比较。结果观察组各种感染性疾病的hs-CRP检测值均显著高于对照组(P<0.01),148例细菌性感染患儿中,hs-CRP阳性143例,阳性率96.6%;白细胞水平升高119例,阳性率80.4%,两种检测值阳性率差异有统计学意义(P<0.01)。结论hs-CRP检测对儿科细菌性感染疾病的诊断和治疗有一定的临床应用价值,可作为诊断小儿细菌性感染和观察疗效的敏感指标。

关 键 词:超敏C-反应蛋白  细菌性感染

Application Value of Determination of Hypersensitive C-Reactive Protein in Paediatric Bacterial Infectious Diseases
YANG Hui-cong,YUAN Min,YANG Cai'e. Application Value of Determination of Hypersensitive C-Reactive Protein in Paediatric Bacterial Infectious Diseases[J]. Modern Diagnosis & Treatment, 2009, 20(5): 268-270
Authors:YANG Hui-cong  YUAN Min  YANG Cai'e
Affiliation:YANG Hui-cong, YUAN Min, YANG Cai' e( 1. Department of Laboratory,Zhangzhou Municipal Hospi- tal,Affiliated to FufianMedical University, Zhangzhou 363000, China; 2. Department of Blood Transfusion, Zhangzhou Municipal Hospital ,Affiliated to Fujian Medical University ,Zhangzhou 363000, China ;3. Technology and Engineering College, Fujian Medical University, Zhangzhou 363000, China)
Abstract:
Objective To study the diagnostic value of determination of hypersensitive C-reactive protein (hs-CRP) in paediatric bacterial infectious diseases. Method 148 cases of bacterial infection (observation group) and 55 eases of healthy children( control group) were enrolled in the study. Serum concentration of hs- CRP was measured with Olympus AU2700 Auomatic Biochemical Analyzer; WBC count was performed with Bayer ADIVA2120 Hematology Analyzer. The results were compared and analyzed between two groups. Results The level of hs-CRP in observation group was obviously higher than that in control group ( P 〈 0.001 ). In observation group, the positive rate of hs-CRP was 96.6% (143/148), and 119 cases(80.4% ) have elevated WBC. There was a statistical difference in two positive rates between two groups( P 〈 0.01 ). Conclusions hs- CRP is valuable in the diagnosis of bacterial paediatric infectious diseases and may be a sensitive index of di- agnosis and efficacy observation of paediatrie bacterial infections diseases.
Keywords:Hypersensitive C-reactive protein  Bacterial infection
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