Enhancement of altered hepatic foci in rat liver and inhibition of intercellular communication in vitro by the pyrethroid insecticides fenvalerate, flucythrinate and cypermethrin |
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Authors: | Hemming, Helena FlodstrOm, Sten Warngard, Lars |
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Affiliation: | Institute of Environmental Medicine, Karolinska Institutet Box 210, S-171 77 Stockholm, Sweden |
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Abstract: | Male Sprague-Dawley rats dosed with N-nitrosodiethylamine (NDEA)24 h after two-thirds partial hepatectomy were treated withthe pyrethroid insecticides fenvalerate, flucythrinate or cypermethrinin the diet: for 20 weeks. Altered hepatic foci were analyzedby quantitative stereology from paraffin-embedded sections stainedfor |
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