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| 红芪多糖对实验性脾虚大鼠胃黏膜中COX-2表达的影响 | |
| 引用本文： | 万生芳,张丽萍,朱建坤,张艳. 红芪多糖对实验性脾虚大鼠胃黏膜中COX-2表达的影响[J]. 西部中医药, 2011, 24(10): 7-10 |
| 作者姓名： | 万生芳 张丽萍 朱建坤 张艳 |
| 作者单位： | 1. 甘肃中医学院,甘肃,兰州,730000 2. 金川集团公司职工医院 |
| 基金项目： | 甘肃省自然科学基金计划科研项目 |
| 摘 要： | 目的:观察红芪多糖对实验性脾虚大鼠胃黏膜组织中COX-2表达的影响.方法:100%大黄水煎液连续42天灌胃制备脾虚证大鼠模型,造模后将大鼠随机分为6组,其中空白对照组、模型对照组正常饲养,药物组(高、中剂量组)用红芪多糖灌胃30天,对照组(高、中剂量组)以黄芪多糖灌胃30天进行干预;用免疫组化法检测大鼠胃黏膜组织中环氧... |
| 关 键 词： | 脾虚证 红芪多糖 COX-2 |
Effects of Hedysarum Polybotys Saccharides on COX-2 Expression in the Gastric Mucosa of PiXu Rat |
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| WAN Sheng-fang,ZHANG Li-ping,ZHU Jian-kun,ZHANG Yan. Effects of Hedysarum Polybotys Saccharides on COX-2 Expression in the Gastric Mucosa of PiXu Rat[J]. Western Journal of Traditional Chinese Medicine, 2011, 24(10): 7-10 | |
| Authors: | WAN Sheng-fang ZHANG Li-ping ZHU Jian-kun ZHANG Yan |
| Affiliation: | WAN Sheng-fang1,ZHANG Li-ping1,ZHU Jian-kun1,ZHANG Yan1 1 Gansu College of TCM,Lanzhou Gansu China 730000,2 Staff Hospital of Jinchuan Group Company |
| Abstract: | Objective:To observe the influence of radix hedysari polysaccharide to expression of COX-2 in gastric mucosa of rat with experimental PiXu.Method:Rats are given intragastric infusion of 100% water decoction of DaHuang continually for 42 days in order to make the models with PiXu.Then the rats are randomly divided into six groups.Rats in model group receive normal feeding,the ones in medication group(high-dose group and middle dose group) are given intragastric infusion of radix hedysari polysaccharide for 3... |
| Keywords: | PiXuZheng radix hedysari polysaccharide COX-2 |
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