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血浆NT-pro BNP和Big ET-1在冠心病的代谢变化及其临床价值
引用本文:陈剑雄,彭紫元,张琼丽,李延武,屠洪,李卓成. 血浆NT-pro BNP和Big ET-1在冠心病的代谢变化及其临床价值[J]. 放射免疫学杂志, 2011, 24(3): 287-290
作者姓名:陈剑雄  彭紫元  张琼丽  李延武  屠洪  李卓成
作者单位:陈剑雄,彭紫元,张琼丽,李延武,李卓成(深圳市第二人民医院检验科,518035);屠洪(深圳市第二人民医院心内科,518035)
摘    要:
目的:探讨冠心病(CHD)患者血浆N末端脑钠肽原(NT-proBNP)与大内皮素-1(Big ET-1)水平的变化及其与心功能的关系.方法:采用酶联免疫吸附试验双抗体夹心法对136例CHD患者及55例健康对照者进行血浆NT-proBNP和Big ET-1测定,同时以彩色多普勒超声心电动仪测定CHD患者左心室舒张末期内径...

关 键 词:N末端脑钠肽  大内皮素  NYHA心功能分级  心血管疾病

Study on Clinical Value of Changes of Plasma NT-proBNP and Big ET-1 in Patients with Coronary Heart Disease
Chen Jian-xiong,Peng Zi-yuan,Zhang Qin-li,et al.. Study on Clinical Value of Changes of Plasma NT-proBNP and Big ET-1 in Patients with Coronary Heart Disease[J]. Journal of Radioimmanology, 2011, 24(3): 287-290
Authors:Chen Jian-xiong  Peng Zi-yuan  Zhang Qin-li  et al.
Affiliation:Chen Jian-xiong1,Peng Zi-yuan1,Zhang Qin-li1,et al.Shenzhen Second People's Hospital,Shenzhen(518035),China
Abstract:
Objective To investigate the changes of plasma levels of N-terminal probrain natriuretic peptide(NT-proBNP) and Big endothelin-1(Big ET-1) and their relationship with cardiac function in patients with coronary heart disease(CHD).Methods The levels of plasma NT-proBNP and Big ET-1 were measured by double antibody enzyme linked immunosorbent assay in 136 patients with CHD and 55 healthy subjects.Left ventricular ejection fraction(LVEF),left ventricular end systolic diameter(LVESD) and left ventricular end dia...
Keywords:NT-proBNP  Big endothelin  NYHA classification  cardiovascular disease  
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