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| 血清总胆汁酸、胆固醇、AST/ALT比值与肝硬化Child-Pugh分级的关系 | |
| 引用本文： | 齐晓丹,沙子健,李兆岩,于海涛.血清总胆汁酸、胆固醇、AST/ALT比值与肝硬化Child-Pugh分级的关系[J].中国医药导报,2010,7(11):13-14,17. |
| 作者姓名： | 齐晓丹 沙子健 李兆岩 于海涛 |
| 作者单位： | 1. 齐齐哈尔医学院生化教研室,黑龙江齐齐哈尔,161006 2. 齐齐哈尔医学院药学实验中心,黑龙江齐齐哈尔,161006 3. 齐齐哈尔医学院第一附属医院检验科,黑龙江齐齐哈尔,161041 4. 齐齐哈尔医学院生物遗传教研室,黑龙江齐齐哈尔,161006 |
| 基金项目： | 黑龙江省青年科学基金项目 |
| 摘 要： | 目的：探讨肝炎后肝硬化患者不同Child-Pugh分级与血清总胆汁酸（TBA）、胆固醇（CHO）、AST/ALT比值的相互关系。方法：选取临床诊断为肝炎后肝硬化患者76例,按Child-Pugh评分进行分级（A、B、C级）;对照组48例为健康体检者,并检测血清TBA、CHO、AST/ALT比值。结果：肝硬化组与对照组比较,血清TBA升高,血清CHO降低,AST/ALT比值升高,差异有高度统计学意义（P〈0.01）。肝硬化患者Child-Pugh分级A、B、C级之间比较,差异有高度统计学意义（P〈0.01）。结论：肝硬化患者血清TBA、CHO、AST/ALT比值联合检测有助于肝硬化患者进行肝功能分级,并有助于评估肝功能受损程度。 |
| 关 键 词： | 肝硬化 Child-Pugh分级 总胆汁酸 胆固醇 AST/ALT比值 |
Relationships of serum total bile acids,cholesterol and AST/ALT ratio with the Child-Pugh classification in cirrhosis |
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| QI Xiaodan,SHA Zijian,LI Zhaoyan,YU Haitao.Relationships of serum total bile acids,cholesterol and AST/ALT ratio with the Child-Pugh classification in cirrhosis[J].China Medical Herald,2010,7(11):13-14,17. | |
| Authors: | QI Xiaodan SHA Zijian LI Zhaoyan YU Haitao |
| Institution: | QI Xiaodan1,SHA Zijian2,LI Zhaoyan3,YU Haitao4(1.Department of Biochemistry,Qiqihar Medical College,Qiqihar 161006,China,2.Department of Experimental Center Pharmacy,3.Department of Laboratory Medicine,the First Affiliated Hospital of Qiqihar Medical College,Qiqihar 161041,4.Department of Bio-Genetics,China) |
| Abstract: | Objective:To study the possible relationships of serum total bile acids (TBA),cholesterol (CHO) and AST/ALT ratio to different Child-Pugh classifications in patients with HBV-related cirrhosis. Methods:Selected clinically diagnosed 76 cases of patients with liver cirrhosis according to Child-Pugh score for classification (grade A,B and C) as the cirrhosis group,48 cases of healthy persons were served as the control group,the serum TBA,CHO and AST/ALT ratio of the two groups were detected. Results:Compared w... |
| Keywords: | Liver cirrhosis Child-Pugh classification Total bile acids Cholesterol AST/ALT ratio |
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