3种结膜囊冲洗液在内眼术前应用的效果分析

目的 探讨既具有清洁结膜囊作用、且刺激性小,也利于环境保护的内眼手术前结膜囊冲洗液在临床应用的方法.方法 排除局部及全身炎性反应,需行内眼手术的患者210例210只眼.随机抽签法分组,A组为实验组用生理盐水200 ml,B组为对照组用0.02%升汞+生理盐水各100 ml.C组为对照组用0.4%庆大霉素液及生理盐水各100 ml冲洗作为结膜囊冲洗液,每组70例70只眼.冲洗前、后用眼拭子采集结膜囊标本并在1 h内送检做细菌培养.分别对3组患者在冲洗后15,30 min结膜充血情况进行比较观察.结果 3组患者在冲洗前细菌阳性率分别为:A组62.86%.B组54.29%.C组50.00%;3组患者冲洗前结膜囊细菌培养阳性率组间比较差异无统计学意义(P>0.05);3组患者冲洗后细菌阳性率分别为:A组31.43%,B组27.14%,C组20.00%;3组患者冲洗后结膜囊细菌培养阳性率组间比较,差异无统计学意义(P>0.05).3组患者结膜囊细菌培养:冲洗前后差异有统计学意义(P<0.05).3组患者冲洗后15 min及30 min结膜充血情况比较:B组的刺激性较大,C组居中.A组刺激性较小. 结论单纯使用生理盐水代替传统的内眼术前结膜囊冲洗液,可减少化学药物对患者眼部的刺激性、毒性等不良反应,减少抗生素的使用,同时可为手术医生提供清晰的手术视野,表明单纯使用生理盐水可以代替传统的内眼结膜囊冲洗液.

Clinical study on three irrigating solution of conjunctival sac before intraocular surgery

Objective To evaluate clinical application of irrigating solution of conjunctival sac be-fore intraocular surgery,which can clean the conjunctival sac with low irritability and low environmental pollution. Methods Patients (210 cases) without systemic inflammatory response and with expected in-traocular surgery were divided into three groups randomly (70 cases in each group). Group A used normal saline(200 ml). Group B used the mixed solution of 0.02% mercury bichloride(100 ml) and normal saline(100 ml). Group C used the mixed solution of 0.4% gentamicin (100 ml) and normal saline (100 ml).The specimens of conjunctival sac were collected and sent to check before and after irrigating.In 15 and 30 min-utes after irrigating,the conjunctival congestions of three groups were compared. Results There was no statistical difference in bacterial positive rate among three groups before and after irrigating:, bacterial posi-tive rate was 62.86% in group A, 54.29% in group B, 50.00% in group C before irrigating; 31.43% in group A, 27.14% in group B, 20.00% in group C after irrigating. There were statistical difference in bacterial cul-ture of conjunctival sac among three groups before and after irrigating (P< 0.05). The comparison of con- junctival congestion: group B had the most serious irritation, group C was median, group A had lightest irri-tation. Conclusions Normal saline as irrigating solution of conjunctival sac for intmecular surgery can reduce chemical irritation and toxicity by reducing use of antibiotics. It can supply clear visual operativefield for doctors so it can substitute traditional irrigating solution of conjunctival sac.