高频电切及热活检灼除治疗胃黏膜脱垂症

目的观察内镜下高频电切及热活检灼除治疗胃黏膜脱垂症的效果。方法胃镜确诊的398例胃黏膜脱垂症患者随机分为高频电切组（161例）、热活检灼除组（185例）和对照组（52例）。治疗组术后和对照组每人每日口服奥美拉唑20mg，连续3周。1个月后行临床症状随访和胃镜复查。结果高频电切组、热活检灼除组和对照组症状随访率分别为96．89％、92．97％和88．46％；随访症状缓解总有效率为85．26％、86．05％和36．96％。治疗组与对照组相比，差异有显著性（P〈0.01）；两治疗组比较差异无显著性（P〉0.05）。高频电切组、热活捡灼除组和对照组胃镜复查率分别为74．53％、73．51％和82。69％；胃镜复查总有效率分别为97．5％、98．53％和13．95％。治疗组与对照组相比．差异有显著性（P〈0.01），两治疗组相比差异无显著性（P〉0.05），但热活检灼除组（92．65％）的显效比例高于高频电切除组（87．5％）（P〈0.01）。结论内镜下热活检灼除法治疗胃黏膜脱垂症易于操作，疗效确切，安全性高。

Investigation into prolapse of gastric mucosa treated by high frequency electrosection and hot biopsy electrocautery

[Objective] To investigate the effects of endoscopic high frequency electrosection and hot biopsy electrocautery on prolapse of gastric mucosa.[Methods] The 398 patients with prolapse of gastric mucosa diagnosed by gastroscopy were randomly divided into electrosection group(n =161),electrocautery group(n =185)and control group(n =52).Every patient had received oral omeprazole 20mg per day for 3 weeks.These patients were followed up the changes of symptoms and gastroscopy after 1 month.[Results] The rate of follow-up symptoms was 96.89%,92.97% and 88.46% respectively and the rate of follow up gastroscopy was 74.53%,73.51% and 82.69% respectively in electrosection,electrocautery and control group after 1 month.Compared with control group(36.96%),the total symptomatic effective rate of electrosection group(85.26%),and electrocautery group(86.05%)significantly increased(P <0.01).There were significant differences between effective rate of endoscopic treatment group and that of control group(13.95%)(P <0.01),no significant difference between total electrosection(97.5%)and electrocautery group(98.53%)(P >0.05),while the proportion rate of endoscopic curative effect in electrocautery group(92.65%)was significantly superior to electrosection group(87.5%)(P<0.01).[Conclusions] The hot biopsy electrocautery which is treated prolapse of gastric mucosa has the characteristics of easy manipulation,certain therapeutic effect and high safety.