肾综合症出血热血清蛋白与肝肾功能及临床关系的研究

目的 了解肾综合症出血热（HFRS）各期血清蛋白的变化特点及其与肝、肾功能的关系。方法 采用瑞士产COBAS MIRA PLUS CC全血动生化分析仪及日本产MA－4210尿液分析仪分别检测同时的空腹静脉血及晨尿。结果 150例HFRS患者217次检测血清总蛋白（T）平均为63.51g/L，白蛋白（A）为36.29g/L，球蛋白（G）为27.22g/L,A/G=1.33。其中A／G为1.49-1.0者137例（63.3%），A／G＜1.0者27例（12.44%），A／G≥1.5者53例（24.42%）。结论 HFRS患者有75.58%存在着低白蛋白血症，并贯穿于各期，异常程度与病情轻重呈正相关，主要原因是肾脏损害，大量白蛋白从尿中丢失，与肝脏的合成功能关系不大。

The relationship between serum protein and hepatorenal functions and clincalmanifestation in hemorragic fever with renal syndrom

Objective: understanding the characteristics of hemorragic fever with renal syndrom(HFRS) and changing on serum protein in each stage and the relationship between liver and kidney. Method: UsingCOBAS MIRA PLUS CC biosynthesis analysing instrument made in Switzerland and MA 4210 urine analysing instrument made in Japan. Results: Average values of total serum protein is 63 51 g/L,albumin(A) is 36 29 g/L,globulin(G) is 27 22 g/L, A/G=1 33 which all is from 150 cases of HFRS patiens by 217 times examined. Among them this value from 137 cases (63 13%) is 1 49 1, 27 cases (12 44%)<1 0, 53 cases (24 42%)>1 5. Conclusion: About 75 58% HFRS pateints have lowwer albumin at each stage and this abnormal level is direcly related to their illness condition. The primary account is because of renal damage in which a lot of albumin lost from urine and this isn't directly related to liver synthesis fuction.