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桥本脑病二例
引用本文:刘芳,孙阳,陈黔妹,董文翊. 桥本脑病二例[J]. 脑与神经疾病杂志, 2012, 20(4): 272-273
作者姓名:刘芳  孙阳  陈黔妹  董文翊
作者单位:清华大学第一附属医院神经内科,北京,100016
摘    要:
目的探讨桥本脑病的临床特点及其治疗方法。方法分析我院收治的2例桥本脑病患者的临床资料。结果两例患者分别以认知功能障碍及癫痫为首发症状,脑脊液检测、脑电图、头颅核磁共振检查未见特异性改变,但是血液甲状腺过氧化物酶抗体(TPOAb)明显增高,例1患者甲状腺功能正常,例2患者有甲亢。2例患者均对皮质类固醇激素敏感。结论临床上有以认知功能障碍、癫痫等症状为突出表现者,须考虑桥本脑病的可能。

关 键 词:桥本脑病  痴呆  癫痫

Two cases of Hashimoto's encephalopathy
LIU Fang , SUN Yang , CHEN Qian-mei , DONG Wen-yi. Two cases of Hashimoto's encephalopathy[J]. Journal of Brain and Nervous Diseases, 2012, 20(4): 272-273
Authors:LIU Fang    SUN Yang    CHEN Qian-mei    DONG Wen-yi
Affiliation:. Department of Neurology,First Hospital of Tsinghua University,Beijing 100016,China
Abstract:
Objective To analyze the clinical characteristic and treatment of Hashimoto’s encephalopathy.Methods The clinical data of two Hashimoto’s encephalopathy patients were retrospectively analyzed.Results Cognitive dysfunction and epilepsy were the first onset of the patients.The result of CSF,EEG and cranial MRI scanning were normal.But serum level of antibodies of thyroid peroxidase(TPoAb) was increasing significantly.One patient’s thyroid function was normal,and the other was hyperthyroid.They were sensitive to corticosteroid.Conclusion Hashimoto’s encephalopathy should be considered when patients are characterized by cognitive impairment and epilepsy.
Keywords:Hashimoto’s encephalopathy  Dementia  Epilepsy
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