老年脑梗死患者认知功能与头颅磁共振成像关系分析

目的探讨老年脑梗死患者梗死部位与认知功能障碍的相关性。方法对80例老年脑梗死患者依据《美国精神障碍诊断与统计手册》对认知功能障碍进行诊断,均用头颅磁共振检查明确病灶部位和范围;同时随机选择无明确梗死灶的80例老人为对照组。用中文版简易智能状态检查表和中文版蒙特利尔认知评估量表分别对两组患者认知功能做联合评估;半年后分别对以上患者复查其认知功能。结果脑梗死患者认知功能障碍的发生率为48.75%,脑梗死组侧别与对照组在认知功能上比较,脑梗死双侧组认识功能障碍发生率高于脑梗死单侧组,左侧脑梗死组认识功能障碍发生率高于右侧组。脑梗死患者中认识功能障碍发生率的次序由高到低为皮质组、丘脑组、基底节及内囊组、脑干组。结论脑梗死患者的认知功能障碍与病灶部位有相关性。

Study of the related factors between location of cerebral infarction and cognitive impairment

Objective To investigate the relationship between the location of cerebral infarction and cognitive impairment.Methods There were studied with the same MRI scanner.80 cerebral infarction patients and other 80 controls were assessed with neuropsychological tests including MiniMental State Examination(MMSE) and Montreal Cognitive Assessment(MOCA) at the stages of 3 weeks and 6 months.Results The incidence of cognitive impairment was 48.75%.Cerebral infarction locus in cerebral,thalamus,basal ganglia and brain stem had correlation with obvious cognitive function impairment.There was significant difference between bilateral and unilateral cerebral infarction in the incidence of cognitive impairment.Conclusion Cognitive function impairment is related to the locus of cerebral infarction.