The effect of oil as a dietary component on in vitro dissolution of an acid-labile drug |
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| Authors: | Al-Behaisi S Antal I Morovján G Marton S Klebovich I |
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| Affiliation: | Research & Development Directorate, EGIS Pharmaceuticals Ltd., Budapest, Hungary. clindev.rd@egis.hu |
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| Abstract: | ![]()
The non-benzodiazepine-like anxiolytic agent deramiclane fumarate (EGIA-3886) was used to demonstrate that the presence of high oil/fat content in dissolution media serves as a barrier against accelerated drug degradation in acidic media. |
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