Intended single-modality management of T1 and T2 tonsillar carcinomas: retrospective comparison of radical tonsillectomy vs radiation from a single institution |
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| Authors: | Lamarre Eric D Seth Rahul Lorenz Robert R Esclamado Ramon Adelstein David J Rodriguez Cristina P Saxton Jerrold Scharpf Joseph |
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| Affiliation: | a Department of Otolaryngology—Head and Neck Surgery, Head and Neck Institute, Cleveland Clinic, Cleveland, OH, USAb Division of Otolaryngology, Head and Neck Surgery, Duke University, Durham, NC, USAc Taussig Cancer Institute Center and Department of Solid Tumor Oncology, Cleveland Clinic, Cleveland, OH, USAd Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA |
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| Abstract: | BackgroundT1 and T2 tonsillar squamous cell cancer with limited neck disease can be managed with single-modality radiation or surgery. Over 11 years, 17 patients underwent radical tonsillectomies; and 33 patients underwent radiation-based treatments for T1 and T2 and N0 to N2a tonsil cancer. Patients were intended to receive single-modality treatment based on presentation; however, some ultimately received adjuvant treatments.MethodsA retrospective chart review to compare overall survival (OS), disease-specific survival (DSS), and locoregional control (LRC) between the groups was used.ResultsIn surgical group, of 17 patients, 11 underwent surgery alone, 3 underwent surgery and radiation, and 3 underwent surgery with concurrent chemoradiation. Five-year OS for the surgical and radiation groups was 93% and 72%, respectively (no significance achieved). Five-year DSS rates (93% and 80%) and LRC (69% and 89%) similarly did not yield any significant difference.ConclusionSurgery remains a viable option in the management of T1 and T2 tonsillar cancers with comparable LRC, OS, and DSS. |
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