Visual recovery after corneal crosslinking for keratoconus: a 1-year follow-up study |
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Authors: | Ivo Guber Josef Guber Claude Kaufmann Lucas M. Bachmann Michael A. Thiel |
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Affiliation: | 1. Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland 3. Eye Clinic, Cantonal Hospital of Winterthur, Brauerstrasse 15, PO 834, CH-8401, Winterthur, Switzerland 2. medignition Inc. Research Consultants, Zug, Switzerland
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Abstract: | Purpose To evaluate visual recovery and intraocular straylight in keratoconus patients 3 months and 1 year after corneal crosslinking (CXL) Patients and Methods Thirty-three eyes of 28 consecutive patients with mild to moderate keratoconus were included. The following were assessed at baseline, 3 months and 1 year after CXL: corrected distance visual acuity (CDVA), intraocular straylight, spherical equivalent (SE), keratometry (Kmax and K min (Diopters D and axis), the regularity index and pachymetry. Changes from baseline were calculated using mixed linear regression models. Results The CDVA remained unchanged 3 months after CXL (-0.003 (95 % CI: -0.038 to 0.044); p?=?0.880) and improved after 1 year (-0.042 (95 % CI: -0.078 to -0.007; p?=?0.021)). The mean straylight value increased significantly by 0.27 (95 % CI: 0.18 to 0.35; p?0.001) 3 months after CX and normalized to preoperative values after 1 year (0.06 (95 % CI: -0.03 to 0.14; p?=?0.215)). SE improved from the mean preoperative value of -2.61 D (95 % CI: -3.83 to -1.39) by 1.95 (95 % CI: 1.03 to 2.86; p?0.001) at 3 months and remained stable at the 1-year follow-up visit (2.17 (95 % CI: 1.21 to 3.12; p?0.001)). Parameters of of keratometry changed only minimally. The regularity index remained almost unchanged at 3 months (2.45 (95 % CI: -4.97 to 9.88; p?=?0.503)) and decreased by 6.97 (95 % CI: -14.08 to 0.14; p?=?0.054). Pachymetry decreased by 44.0 μm (95 % CI: 56.1 to 31.9; p?0.001) at 3 months and almost returned to preoperative values at 12 months (-11.3 μm (95 % CI: -27.9 to 5.3; p?=?0.175)). Conclusions In accordance with the decrease in CDVA and patients’ complaints of disability due to glare, intraocular straylight increased 3 months after surgery. One year after CXL, there was an increase in CDVA due to an improved SE and regularity index, and intraocular straylight had normalized. |
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