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Visual recovery after corneal crosslinking for keratoconus: a 1-year follow-up study
Authors:Ivo Guber  Josef Guber  Claude Kaufmann  Lucas M. Bachmann  Michael A. Thiel
Affiliation:1. Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland
3. Eye Clinic, Cantonal Hospital of Winterthur, Brauerstrasse 15, PO 834, CH-8401, Winterthur, Switzerland
2. medignition Inc. Research Consultants, Zug, Switzerland
Abstract:

Purpose

To evaluate visual recovery and intraocular straylight in keratoconus patients 3 months and 1 year after corneal crosslinking (CXL)

Patients and Methods

Thirty-three eyes of 28 consecutive patients with mild to moderate keratoconus were included. The following were assessed at baseline, 3 months and 1 year after CXL: corrected distance visual acuity (CDVA), intraocular straylight, spherical equivalent (SE), keratometry (Kmax and K min (Diopters D and axis), the regularity index and pachymetry. Changes from baseline were calculated using mixed linear regression models.

Results

The CDVA remained unchanged 3 months after CXL (-0.003 (95 % CI: -0.038 to 0.044); p?=?0.880) and improved after 1 year (-0.042 (95 % CI: -0.078 to -0.007; p?=?0.021)). The mean straylight value increased significantly by 0.27 (95 % CI: 0.18 to 0.35; p?p?=?0.215)). SE improved from the mean preoperative value of -2.61 D (95 % CI: -3.83 to -1.39) by 1.95 (95 % CI: 1.03 to 2.86; p?p?p?=?0.503)) and decreased by 6.97 (95 % CI: -14.08 to 0.14; p?=?0.054). Pachymetry decreased by 44.0 μm (95 % CI: 56.1 to 31.9; p?p?=?0.175)).

Conclusions

In accordance with the decrease in CDVA and patients’ complaints of disability due to glare, intraocular straylight increased 3 months after surgery. One year after CXL, there was an increase in CDVA due to an improved SE and regularity index, and intraocular straylight had normalized.
Keywords:
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