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| 吴茱萸次碱的研究进展 | |
| 引用本文： | 余奇,郭澄,程泽能.吴茱萸次碱的研究进展[J].药学实践杂志,2007,25(6):353-357. |
| 作者姓名： | 余奇 郭澄 程泽能 |
| 作者单位： | 1. 上海交通大学附属第六人民医院药剂科,上海,200233;中南大学药学院药物动力学研究所,湖南,长沙,410013 2. 上海交通大学附属第六人民医院药剂科,上海,200233 3. 中南大学药学院药物动力学研究所,湖南,长沙,410013 |
| 摘 要： | 吴茱萸次碱是中药吴茱萸中的主要有效成分,本文介绍了近十余年来国内外对吴茱萸次碱的研究进展,包括合成、对药物代谢酶的影响、代谢机制和药理作用等。 |
| 关 键 词： | 吴茱萸次碱 合成 细胞色素P450 降钙素基因相关肽 药理作用 |
| 文章编号： | 1006-0111（2007）06-0353-05 |
| 收稿时间： | 2007-02-01 |
| 修稿时间： | 2007年2月1日 |
Current advances in the study on rutaecarpine |
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| YU Qi,GUO Cheng and CHENG Ze-neng.Current advances in the study on rutaecarpine[J].The Journal of Pharmaceutical Practice,2007,25(6):353-357. | |
| Authors: | YU Qi GUO Cheng and CHENG Ze-neng |
| Institution: | Department of Pharmacy,Shanghai Sixth People's Hospital,Shanghai JiaoTong University,Shanghai 200233,China;Department of Pharmacokinetics,School of Pharmaceutical Sciences,Central South University,Changsha 410013,China.;Department of Pharmacy,Shanghai Sixth People's Hospital,Shanghai JiaoTong University,Shanghai 200233,China;Department of Pharmacokinetics,School of Pharmaceutical Sciences,Central South University,Changsha 410013,China.;Department of Pharmacy,Shanghai Sixth People's Hospital,Shanghai JiaoTong University,Shanghai 200233,China;Department of Pharmacokinetics,School of Pharmaceutical Sciences,Central South University,Changsha 410013,China.;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Pharmacology,School of Pharmacy,Second Military Medical University,Shanghai 200433,China;Department of Epidemiology Second Military Medical University,Shanghai 200433,China;3.The 411th Hospital of PLA,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Department of Medicinal Chemistry,Pharmacy School,Second Military Medical University,Shanghai 200433,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Institute of Pharmacology,North Sichuan Medical College,Nanchong 637007,China;Department of Pharmacy,No.451 Hospital of PLA,Xi'an 710000,China;Department of Pharmacy,General Hospital of Lanzhou Command of PLA,Lanzhou 730050,China;Department of Pharmacy,No.451 Hospital of PLA,Xi'an 710000,China;Department of Pharmacy,General Hospital of Lanzhou Command of PLA,Lanzhou 730050,China;Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China;Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China;Dept.of Pharmacy,General Hospital of Beijing Military Region,Beijing100700, China;Dept.of Pharmacy,General Hospital of Beijing Military Region,Beijing100700, China;Dept.of Pharmacy,General Hospital of Beijing Military Region,Beijing100700, China;Dept.of Pharmacy,General Hospital of Beijing Military Region,Beijing100700, China;Dept.of Pharmacy,General Hospital of Beijing Military Region,Beijing100700, China;Zhejiang Institute for Drug Control,Hangzhou 310004,China;Zhejiang Institute for Drug Control,Hangzhou 310004,China;Department of Pharmacy,Tongde Hospital of Zhejiang Province,Hangzhou310012,China;Second bureau of drugs,general hospital of Chinese PLA,Beijing 100853,China;3rd Hospital of PLA,Baoji 721004,China;3rd Hospital of PLA,Baoji 721004,China;3rd Hospital of PLA,Baoji 721004,China;3rd Hospital of PLA,Baoji 721004,China;Department Pharmacy,General Hospital of PLA,Beijing 100853,China;Department Pharmacy,General Hospital of PLA,Beijing 100853,China;No.303 Hospital of PLA,Nanning 530021,China |
| Abstract: | The rutaecarpine is an effective component from Evodia rutaecarpa(Juss.) Benth.Current advances in the study of rutaecarpine is reviewed,including synthesize,effects on metabolizing enzyme,metabolic mechanism, pharmacological activity,etc. |
| Keywords: | rutaecarpine synthesize CYP450 CGRP pharmacological activity |
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