原发性甲状旁腺功能亢进症五例误诊分析

目的探讨原发性甲状旁腺功能亢进症(primary Hyperparathyroidism,PHPT)的误诊原因,提出减少误诊的对策。方法回顾分析5例PHPT误诊的临床资料。结果本组表现为四肢关节疼痛5例,伴随多发肾结石3例,多发性病理骨折2例,四肢肌肉疼痛伴肌无力1例。5例分别误诊为肌营养不良、病理性骨折、肾结石、骨质疏松、风湿性关节炎等,部分病例多次误诊。5例查血钙、血磷异常,甲状旁腺激素明显升高,经颈部B超或CT检查发现甲状旁腺肿瘤,均接受手术治疗,术后病理诊断均为甲状旁腺腺瘤。结论临床医生应提高对PHPT的认识,对疑诊患者早期检测血钙、血磷和甲状旁腺激素,行颈部B超和CT检查定位诊断,降低误诊率。

Misdiagnosis Analysis of 5 Patients with Primary Hyperparathyroidism

Objective To investigate the misdiagnosis cause of primary hyperparathyroidism(PHPT),and to propose measures to reduce misdiagnosis.Methods The clinical data of 5 patients with PHPT were retrospectively analyzed.Results 5 patients had pain in the limbs and joints,3 had multiple kidney calculi,2 had multiple pathologic fractures,and 1 had muscles pain in limbs with muscle weakness.The patients were misdiagnosed as having muscular dystrophy,pathologic fracture,kidney calculi,osteoporosis,rheumatic arthritis r...