瑞替普酶治疗急性心肌梗死的临床观察与护理探讨

目的 探讨瑞替普酶治疗急性心肌梗死的疗效及护理.方法 将174例急性心肌梗死患者分为瑞替普酶溶栓组(A组)与尿激酶溶栓组(B组).比较两组患者的冠状动脉再通率、并发症与不良反应发生率,并总结其护理体会.结果 冠状动脉再通率:A组为86.6％,B组为53％,A组高于B组(P＜0.05)；再通所需时间:A组为(61土22)min,B组为(88±29)min,A组少于B组(P＜0.05)；再灌注心律失常发生率:A组为59.8％,B组为37.1％,A组高于B组(P＜0.05).结论 瑞替普酶用于AMI再灌注治疗安全有效,合理安排护理措施,用敏捷、准确、专业的方式处理紧急情况,对溶栓成功非常重要,加强护理可提高疗效,降低病死率.

OBSERVATION AND NURSING FOR PATIENTS WITH ACUTE MYOCARDIAL INFARCTION TREATED WITH RETEPLASE

Objective To investigate the clinical effect and nursing measures for patients with acute myocardial infarction treated with reteplase.Methods 174 cases with AMI were divided into the reteplase thrombolysis group(Group A) and the urokinase thrombolysis group(Group B).The rates of reperfusion arrhythmia,complications and the side effect of the two groups were compared and nursing experience was summarized.Results The rate of coronary artery patency was 86.6% in Group A and 53% in Group B(P<0.05).The time needed for coronary artery patency was(61±22)min in Group A and(88±29)min in Group B(P<0.05).The rate of reperfusion arrhythmia was 59.8% in Group A and 37.1% in Group B(P<0.05).Conclusion The use of reteplase is safe and effective in the treatment for AMI reperfusion.Quick,accurate disposal of emergency is vital to the success in treating thrombolysis.The therapeutic effect can be improved and the rate of death can be declined by intensive nursing care.