壳多糖对创伤愈合作用的形态学观察

通过大白兔背部的创伤实验，对比观察了壳多糖对伤口愈合的作用。肉眼、光镜、电镜及免疫组化观察表明：壳多糖具有明显的诱导局部巨噬细胞增多、巨噬细胞吞噬能力增强、促进伤口收缩及愈合的作用；与云南白药组和空白对照组相比有显著差异。探讨了壳多糖促进伤口愈合的机理。

Morphological Observation of Chitin in Wound Healing

rabbites were wounded on the back.Each one had 3 wounds that were treated separately with chitin and Yunnan Baiyao.Microscopically,results showed woundtreated with chitin had more macrophages and myofibroblasts than those treated with Yunnan Baiyao and the empty control group Thus healing of wound was advanced and woundwas contracted.We sugest that myofibroblasts containing actin had the effect for wound contraction and the basal cells of squamous cell epithelium containing actin migrated toward the wound and finally covered the wound.