首页 | 本学科首页   官方微博 | 高级检索  
     


Pulmonary sequestration in infants and children: a 20-year experience and review of the literature
Authors:C G DeParedes  W S Pierce  D G Johnson  J A Waldhausen
Affiliation:1. Centre Chirurgical Marie Lannelongue, Département de Pathologie, Le Plessis Robinson, France;2. Hôpital Louis-Pradel, Département de Pathologie, Lyon, France;3. Chu de Tours, Département de Pathologie, Tours, France;4. Hôpital Pasteur, CHU de Nice, Laboratoire de Pathologie Clinique et Expérimentale, Nice, France;5. CHU de Grenoble, Département d’Anatomie et de Cytologie Pathologiques, Grenoble, France;6. CHU de Bordeaux, Dr Parrens: EA 2406 Département de Pathologie, Bordeaux, France;7. Hôpital Nord, APHM, Laboratoire d’Anatomie Pathologique, Marseille, France;8. CHU Rangueil, Service d’Anatomie Pathologique, Toulouse, France;9. Hôpital Louis-Pradel, Hospices Civils de Lyon, Département des Maladies Respiratoires, Lyon, France;10. Institut Gustave Roussy, Département de Médecine, Villejuif, France;11. Centre Universitaire Médical de Mannheim, Université de Heidelberg, Institut de Pathologie, Mannheim, Germany;12. Université Paris Descartes, Sorbonne Paris Cité, Service de Pathologie, AP-HP Hôpital Necker Enfants Malades, Paris, France;1. Divisions of Cardiovascular Medicine, Imperial College Healthcare NHS Trust;2. Respiratory Medicine, Imperial College Healthcare NHS Trust;3. Clinical Chemistry, Imperial College Healthcare NHS Trust;4. Imaging, Imperial College Healthcare NHS Trust;5. National Heart and Lung Institute Cardiovascular Sciences, Imperial College London, London, England;6. Respiratory Sciences, Imperial College London, London, England;8. Imperial College School of Medicine, Imperial College London, London, England;1. Division of Hematology/Oncology, Department of Internal Medicine, Tufts University School of Medicine, Boston, MA;2. Division of Hematology/Oncology, Department of Internal Medicine, Tufts Cancer Center, Boston, MA;3. Department of Internal Medicine, Tufts Medical Center, Boston, MA;4. The Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA;5. Tufts Clinical and Translational Sciences Institute, Tufts University, Boston, MA
Abstract:
Pulmonary sequestration is a relatively rare condition in which a portion of lung tissue develops without communication with the tracheobronchial tree or the pulmonary artery. Blood supply is derived from one or more branches of the aorta. Its embryogenesis is uncertain, but it occurs in two forms, extralobar (ELS) and intralobar (ILS).In ELS the abnormal lung tissue is completely separate from the normal lung. It occurs in males four times as frequently as in females and is usually discovered in infancy. It is associated with an ipsilateral diphragmatic hernia in the majority of cases, and occasionally bronchial connections from the ELS to the esophagus or stomach have been described. ELS almost always occurs on the left side and, rarely, may be found below the diaphragm. Venous drainage is to the systemic veins or to the portal system. The ELS itself usually does not become diseased; symptoms are produced either by cystic degeneration and resultant compression of adjacent lung or by an associated diaphragmatic hernia.On the other hand, ILS typically occurs in the posterior basal segment of one of the lower lobes, most often the left. It occurs in males and females with equal frequency, and usually it makes its appearance later in childhood. Only very occasionally are associated anomalies present. Venous drainage is to the inferior pulmonary vein together with the rest of the lower lobe. The sequestered segment very frequently becomes infected and gives rise to symptoms of pneumonia. Arteriography is useful in diagnosis, and segmental resection or lobectomy is the indicated treatment.
Keywords:
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号