多囊卵巢综合征生殖障碍表现为天癸失序

中医学多从月经病、不孕等生殖障碍疾病诊治多囊卵巢综合征（polycystic ovary syndrome,PCOS）。PCOS的生殖障碍,主要特征为卵巢雄激素过多及卵泡发育障碍,临床表现为月经后期、月经过少、闭经和不孕等。胰岛素抵抗是其关键病理机制。天癸是促进人体生长、发育和生殖机能,维持妇女月经和胎孕所必须的物质,天癸异常（包括时限、状态、节律）与女性生殖障碍关系密切。卵巢是PCOS治疗的靶器官,其功能特征符合女性天癸的特点,即具有时限性、状态性和节律性,PCOS卵巢功能障碍,表现为典型的＂天癸失序＂。

Disorder of Tiangui (kidney essence) and reproductive dysfunction in patients with polycystic ovary syndrome

Traditional Chinese medicine (TCM) usually views polycystic ovary syndrome (PCOS) as a menstrual disease or infertility disease. Reproductive dysfunction in PCOS is characterized by ovarian androgen excess and disturbance of follicular development, and its main clinical manifestations include delayed menstruation, scant menstruation, amenorrhea or infertility. Insulin resistance is a key pathological mechanism of PCOS. "Tiangui" (kidney essence) as a sex-stimulating essence in female in TCM theory, is essential to the menstruation and pregnancy of women. The disturbance of Tiangui (including time, status and rhythm) would result in female reproductive problems. Current studies of Tiangui indicate that ovary is the target organ of PCOS treatment, and its functional characteristics are consistent with the properties of Tiangui in time frame, state form and rhythm cycle. It is then concluded that ovarian dysfunction in PCOS can be expressed as disorder of Tiangui.