阻塞性睡眠呼吸暂停低通气综合征与心律失常

睡眠相关的呼吸紊乱在已确诊的心血管疾病患者中高度流行,阻塞性呼吸暂停在睡眠中引起间歇性的低氧血症和二氧化碳潴留,在自主神经功能、血管活性物质、炎症、氧化应激、内皮功能、血栓形成、胸腔压力等病理生理方面促进了心脏和血管疾病的发生,与心律失常有着密切的关系。

The Relationship between the Obstructive Sleep Apnea Hypopnea Syndrome and Arrhythmias

Sleep-related breathing disorders are highly prevalent in patients with established cardiovascular disease.Obstructive apneas may induce severe intermittent hypoxemia and CO2 retention during sleeping,and can promote cardiac and vascular disease in terms of the following aspects:the sympathovagal function,vasoactive substances,inflammation,oxidative stress,endothelial dysfunction,thrombosis,intrathoracic pressure changes,thus it is closely related to arrhythmias.