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Duration of Vi antibodies in participants vaccinated with Typhim Vi (Typhoid Vi polysaccharide vaccine) in an area not endemic for typhoid fever
Authors:James E. Froeschle  Michael D. Decker
Affiliation:1. Scientific and Medical Affairs, sanofi pasteur, Swiftwater, PA, United States;2. Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, TN, United States
Abstract:
After a single injection of Typhim Vi® (typhoid Vi polysaccharide vaccine), serum antibody concentrations were monitored for 3 years in 37 adults who resided where typhoid fever was not endemic. Anti-Vi antibody concentrations declined progressively during the study, to levels that support the current US recommendation for revaccination every 2 years.
Keywords:Vaccines   Vi polysaccharide vaccine   Typhoid   Bacterial Polysaccharides
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