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伊贝沙坦对原发性高血压患者左室结构和功能的影响
引用本文:罗康华,黄子扬. 伊贝沙坦对原发性高血压患者左室结构和功能的影响[J]. 九江医学, 2003, 18(3): 136-138
作者姓名:罗康华  黄子扬
作者单位:九江学院附属医院,九江,332000;福建医科大学附属二院心内科
摘    要:目的研究国产新型血管紧张素Ⅱ受体拮抗剂(AⅡRA)伊贝沙坦对原发性高血压患者左室结构和功能的影响.方法应用2-D多普勒超声心动图观察30例原发性高血压患者口服伊贝沙坦(150~300 mg/d)治疗前后左室结构和功能的变化.结果原发性高血压患者经伊贝沙坦治疗16周后左室重量及其指数明显降低(P<0.05),心脏舒张功能明显改善(P<0.05).结论伊贝沙坦能逆转左室重构,改善左心舒张功能.

关 键 词:伊贝沙坦  原发性高血压  左室结构  左室功能  超声心动图
修稿时间:2002-12-20

EFFECT OF IRBESARTAN ON LEFT VENTRICULAR STRUCTURE AND FUNCTION IN ESSENTIAL HYPERTENSIVE PATIENTS
Luo kanghua,Huang ZiyangJiujiang University Medical College. EFFECT OF IRBESARTAN ON LEFT VENTRICULAR STRUCTURE AND FUNCTION IN ESSENTIAL HYPERTENSIVE PATIENTS[J]. Jiujiang Medical Journal, 2003, 18(3): 136-138
Authors:Luo kanghua  Huang ZiyangJiujiang University Medical College
Affiliation:Jiujiang 332000
Abstract:Objective:To observe the effect of irbesartan, a new angiotensin II receptor antagonist, on left ventricular structure and function in essential hypertensive patients. Method: The left ventricular structure and function were observed in 30 essential hypertensive patients by 2 - D Doppler echocardiography before and after 16 - week treatment with irbesantan (150-300mg daily). Results: After treatment with irbesartan for 16 weeks, left ventricular weight and index in EH patients significantly decreased (P<0.05), while cardiac diastolic function was obviously improved (P<0.05). Conclusion: Irbesartan can improve left ventricular remodeling and diastolic function.
Keywords:irbesartan  hypertension  ventricular structure   left  ventricular function   left  echocardiography
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