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| 地肤叶水提物对四氧嘧啶致糖尿病小鼠降糖作用的观察 | |
| 引用本文： | 郭笑冬,张艳,林红伍,李玉叶,邵岩,丁怀莹,王士贤,李庆选. 地肤叶水提物对四氧嘧啶致糖尿病小鼠降糖作用的观察[J]. 世界中医药, 2011, 6(3): 258-259 |
| 作者姓名： | 郭笑冬 张艳 林红伍 李玉叶 邵岩 丁怀莹 王士贤 李庆选 |
| 作者单位： | 天津市塘沽区中医医院,天津市塘沽区新河街杭州道78号,300451 |
| 基金项目： | 湖南省科学技术厅重大项目 |
| 摘 要： | 目的：探讨地肤叶水提物对糖尿病小鼠的降糖作用。方法：通过标准化四氧嘧啶造模糖尿病小鼠。选取血糖相近的小鼠分3组进行实验,分别喂药10天、10天、7天后观察实验组降糖结果,进行统计分析;并对实验小鼠进行毒理学实验。结果：地肤叶水提物剂量在4·0g/kg灌胃给药,7～10日均有一定降糖作用,与对照组比较可下降20%左右,最高达34·5%。结论：地肤叶水提物具有一定降糖作用,且不具有明显的毒副作用。 |
| 关 键 词： | @地肤 糖尿病小鼠 降血糖 |
| 收稿时间： | 2010-03-08 |
Impact of Difuye extract from Water on Alloxan-induced Diabetes Mice |
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| Guo Xiaodong,Zhang Yan,Lin Hongwu. Impact of Difuye extract from Water on Alloxan-induced Diabetes Mice[J]. World Chinese Medicine, 2011, 6(3): 258-259 | |
| Authors: | Guo Xiaodong Zhang Yan Lin Hongwu |
| Affiliation: | Guo Xiaodong,Zhang Yan,Lin Hongwu (Tianjin Tanggu Hospital of Chinese Medicine,Post code：300451) |
| Abstract: | Objective：To explore anti-diabetic effect of Difuye extract from water on diabetic mice model.Methods：Alloxan-induced diabetes mice with similar glucose values were selected,and given test extract for respectively 10 and 7 days,observed glucose values;carried out statistic analysis;and performed toxic experiment.Results：Anti-diabetic effect was shown after the extract was given 4.0g/kg intragastrically for 7-10 days,which was about 20% decrease,and 20% at most compared with glucose values of the control group.Conclusion：Difuye extract from water has definite anti-diabetic effect and no obvious side effects. |
| Keywords: | Difu Diabetic mice Anti-diabetic |
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