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不同波形强度低频电刺激局灶性脑缺血大鼠颈部同体质量、肝肾功能及死亡率的变化
引用本文:杨永红,何成奇,杨霖,高强,李莎莎,何竟.不同波形强度低频电刺激局灶性脑缺血大鼠颈部同体质量、肝肾功能及死亡率的变化[J].中国神经再生研究,2011,6(4):304-308.
作者姓名:杨永红  何成奇  杨霖  高强  李莎莎  何竟
作者单位:四川大学华西医院康复科,四川大学华西医院康复医学科,四川大学华西医院康复医学科,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China
基金项目:supported by the National High Technology Research and Development Program of China(The development and application of novel techniques for cerebrovascular disease rehabilitation),No.2007AA02Z482
摘    要:Low-frequency electrical stimulation has resulted in favorable effects in the treatment of post-stroke dysphagia.However,the safety of cervical low-frequency electrical stimulation remains unclear because of numerous nerves and blood vessels in the neck.In the present study,rats with ischemic stroke underwent low-frequency electrical stimulation,and systemic and local effects of electrical stimulation at different densities and waveforms were investigated.Electrical stimulation resulted in no significant effects on body mass,liver or kidney function,or mortality rate.In addition,no significant adverse reaction was observed,despite overly high intensity of low-frequency electrical stimulation,which induced laryngismus,results from the present study suggested that it is safe to stimulate the neck with a low-frequency electricity under certain intensities.

关 键 词:adverse  reaction  deglutition  rehabilitation  low-frequency  electrical  stimulation  ischemic  stroke  rats

Effects of cervical low-frequency electrical stimulation with various waveforms and densities on body mass, liver and kidney function, and death rate in ischemic stroke rats
Yonghong Yang,Chengqi He,Lin Yang,Qiang Gao,Shasha Li,Jing He.Effects of cervical low-frequency electrical stimulation with various waveforms and densities on body mass, liver and kidney function, and death rate in ischemic stroke rats[J].Neural Regeneration Research,2011,6(4):304-308.
Authors:Yonghong Yang  Chengqi He  Lin Yang  Qiang Gao  Shasha Li  Jing He
Institution:Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China,Department of Rehabilitation Medicine, West China Hospital, Sichuan University, Key Laboratory of Rehabilitation Medicine of Sichuan Province, Chengdu 610041, Sichuan Province, China
Abstract:Low-frequency electrical stimulation has resulted in favorable effects in the treatment of post-stroke dysphagia. However, the safety of cervical low-frequency electrical stimulation remains unclear because of numerous nerves and blood vessels in the neck. In the present study, rats with ischemic stroke underwent low-frequency electrical stimulation, and systemic and local effects of electrical stimulation at different densities and waveforms were investigated. Electrical stimulation resulted in no significant effects on body mass, liver or kidney function, or mortality rate. In addition, no significant adverse reaction was observed, despite overly high intensity of low-frequency electrical stimulation, which induced laryngismus, results from the present study suggested that it is safe to stimulate the neck with a low-frequency electricity under certain intensities.
Keywords:adverse reaction  deglutition rehabilitation  low-frequency electrical stimulation  ischemic stroke  rats
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