| 体外受精中的受精失败 |
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| 引用本文： | 刘平,郑晓英.体外受精中的受精失败[J].生殖医学杂志,2011,20(2):108-111. |
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| 作者姓名： | 刘平 郑晓英 |
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| 作者单位： | 北京大学第三医院生殖医学中心,北京,100191 |
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| 摘 要： | 受精是雌雄配子结合形成合子的过程,它标志着一个新生命的开始,是自然界最神秘和复杂的事件之一.受精失败（Total fertilization failures, TFF）特指在体外受精（in vitro fertilization, IVF）培养过程的一定时段内包括常规受精和卵胞浆内单精子注射（ICSI）],精卵没能结合为合子,形态学上没有看到精原核和卵原核形成的状态.
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| 关 键 词： | 受精 完全受精失败 补救卵胞浆内单精子注射 卵母细胞激活 |
Total fertilization failure during in vitro fertilization |
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| LIU Ping,ZHENG Xiao-ying.Total fertilization failure during in vitro fertilization[J].Journal of Reproductive Medicine,2011,20(2):108-111. |
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| Authors: | LIU Ping ZHENG Xiao-ying |
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| Institution: | (Reproductive Medicine Center, Third Hospital of Peking University, Beijing 100191) |
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| Abstract: | Total fertilization failures （TFF） are rare events of in vitro fertilization （IVF）. Most cases occur due to lack or dysfunction of sperm binding to/penetrating the zona pellucida or failure of oocyte activation. Fertilization failure is not predictable because of lacking an accurate and sensitive method. The clinical value of rescue intracytoplasmic sperm injection （ICSI） should be carefully considered according to patient＇s history, clinical characteristics |
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| Keywords: | Fertilization Total and gametes quality fertilization failure Rescue ICSI Oocyte activation |
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