Preparation and ESCA characterization of poly(vinyl chloride) surf ace-grafted with heparin-complexing poly(amido amine) chains |
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| Authors: | P. Ferruti R. Barbucci N. Danzo A. Torrisi O. Puglisi S. Pignataro P. Spartano |
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| Affiliation: | Istituto di Chimica degli Intermedi, Via Risorgimento 4, 40186 Bologna, Italy;Istituto di Chimica Generale dell'' Università, Via Piano del Mantellini 44, 53100 Siena, Italy;Istituto di Chimica Dipartimentale, Viale Andrea Doria, 95100 Catania, Italy;Istituto di Chirurgia del Cuore e del G. V., Policlinico Umberto I, Università — 00100 Roma, Italy |
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| Abstract: | ![]()
By a simple process poly(amido-amine) chains have been grafted on the surface of poly(vinyl chloride). Grafted poly(vinyl chloride) is able to adsorb heparin, thus providing potentially non-thrombogenic surfaces. The grafting of poly(amido-amine), and the heparin adsorption have been studied by ESCA. It has been found that the total amount of grafted poly(amido-amine) depends on the molecular weight of the poly(amido-amine) used in the grafting reaction, but the amount of heparin adsorbed on the grafted material is relatively independent of the length of the poly(amido-amine) grafted chains. |
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| Keywords: | blood surface preoperties spectroscopy poly (vinyl chloride) poly (am/do amine) heparinization ESCA |
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