人参皂苷三醇型与二醇型在不同量比下对大鼠机体燥性的影响研究

目的 探究人参皂苷三醇型与人参皂苷二醇型含量比值变化对大鼠机体的燥性影响.方法 将30只SD大鼠随机分为空白组和4个实验组(R值=0.5、1、1.5、2),每组6只.采用Elisa法测定大鼠血中Na+-K+-ATP酶、Ca2+-Mg2+-ATP酶、乳酸脱氢酶(LDH)、琥珀酸脱氢酶(SDH)以及脑中胆碱酯酶(ChE)、...

Study on the effect of ginsenoside triol type and glycol type on dryness of rats in different dosage ratios

Objective To explore the effect of the content ratio of ginsenotriol type to ginsenodiol type on dryness of the body.Methods 30 SD rats were randomly divided into blank group and 4 experimental groups(R value=0.5,1,1.5,2),with 6 rats in each group.The contents of Na⁺-K⁺-ATPase,Ca²⁺-Mg²⁺-ATPase,lactate dehydrogenase(LDH),succinate dehydrogenase(SDH)and cholinesterase(ChE)and acetylcholinesterase(AChE)in the brain of rats were determined by ELISA,and the effects of ginsenoside triol and diol on energy metabolism,material metabolism and central nervous excitation of SD rats were observed.Results Compared with the blank group,the indexes of Na⁺-K⁺-ATPase and Ca²⁺-Mg²⁺-ATPase in R=1.5 group and R=1.0 group increased significantly;In the detection of nerve excitation index in rat brain,compared with the blank group,the Che index in R=0.5 group and R=1.5 group decreased significantly;R=2.0 group decreased significantly in ache index.Conclusion The ginsenoside content ratio of different ginsenosides has a certain correlation with ginseng dryness.When ginsenoside content ratio was higher,the energy metabolism and material metabolism of the body increased,the excitability of the central nervous system increased,and the dryness of ginseng increased.