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| 甲状腺乳头状癌颈部淋巴结转移规律临床分析 | |
| 引用本文： | 张强,张仑,宋方方,张文超,姚晓峰,张浏阳,陈可欣. 甲状腺乳头状癌颈部淋巴结转移规律临床分析[J]. 中国耳鼻咽喉头颈外科, 2010, 17(12): 639-642 |
| 作者姓名： | 张强 张仑 宋方方 张文超 姚晓峰 张浏阳 陈可欣 |
| 作者单位： | 天津市肿瘤防治重点实验室,天津医科大学附属肿瘤医院头颈一科,天津,300060;天津市肿瘤防治重点实验室,天津医科大学附属肿瘤医院流行病学室,天津,300060 |
| 摘 要： | 目的探讨甲状腺乳头状癌（papillary thyroid carcinoma,PTC）颈部淋巴结转移规律及清扫范围的合理选择,提高患者生存质量。方法回顾性分析我院2007年10月～2009年9月收治的160例行功能性颈部淋巴结清扫术（functional node dissection,FND）患者,按VI区阳性淋巴结数由少到多分为4组：组1（对照组）,54例患者,淋巴结数0个;组2,52例患者,淋巴结数1～2个;组3,28例患者,淋巴结数3～4个;组4,26例患者,淋巴结数≥5个。应用χ2检验和Logistic回归方法分析比较各组淋巴结转移规律。结果性别、年龄、体重指数与II～IV区淋巴结转移无关（P均〉0.05）,原发灶侵及范围和VI区阳性淋巴结数均与II～IV区淋巴结转移有关（χ2=8.025,P〈0.05;χ2=17.234,P〈0.05）。诸因素与V区淋巴结转移的关系无关（P均〉0.05）。另随VI区阳性淋巴结数增加,II～IV区淋巴结转移相对危险度依次增加,肿物范围侵出腺叶时患者II～IV区淋巴结转移是腺内II～IV区淋巴结转移风险的2.48倍。结论 PTC原发灶侵及范围及VI区淋巴结转移情况对II～IV区淋巴结转移的影响有统计学意义,并随VI区阳性淋巴结数增加,II～IV区淋巴结转移相对危险度依次增加。淋巴结转移规律研究可为临床合理选择颈部淋巴结清扫范围、选择更适宜的术式提供依据,进一步提高患者生存质量。 |
| 关 键 词： | 甲状腺肿瘤 颈淋巴结清扫术 预后 淋巴转移 |
Characteristics of cervical lymph node metastasis of papillary thyroid carcinoma |
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| ZHANG Qiang,ZHANG Lun,SONG Fangfang,ZHANG Wenchao,YAO Xiaofeng,ZHANG Liuyang,CHEN Kexin. Characteristics of cervical lymph node metastasis of papillary thyroid carcinoma[J]. Chinese Archives of Otolaryngology-Head and Neck Surgery, 2010, 17(12): 639-642 | |
| Authors: | ZHANG Qiang ZHANG Lun SONG Fangfang ZHANG Wenchao YAO Xiaofeng ZHANG Liuyang CHEN Kexin |
| Affiliation: | ZHANG Qiang1,ZHANG Lun1,SONG Fangfang2,ZHANG Wenchao1,YAO Xiaofeng1,ZHANG Liuyang1,CHEN Kexin2(1 Department of Head and Neck Surgery,2 Department of Epidemiology and Biostatistics,Tianjin Medical University Cancer Hospital and Institute,Tianjin,300060,China) |
| Abstract: | OBJECTIVE To study the regularity of cervical lymph node metastasis of papillary thyroid carcinoma and select a reasonable extent of lymph node dissection in order to improve the quality of life of patients.METHODS One hundred and sixty cases were collected in this study.All the patients underwent functional neck dissection from October 2007 to September 2009 in our hospital.Before surgery,all patients had not received neck dissection.One hundred and fifty eight cases underwent unilateral FND(11 cases under... |
| Keywords: | Thyroid Neoplasms Neck Dissection Prognosis Lymphatic Metastasis |
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