Glial and neuronoglial malformative lesions associated with medically intractable epilepsy |
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| Authors: | A. Vital C. Marchal H. Loiseau A. Rougier J. M. Pedespan J. Rivel C. Vital |
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| Affiliation: | (1) Service de Neuropathologie, Hôpital Pellegrin, F-33076 Bordeaux Cedex, France;(2) Department of Neurology, Bordeaux II University, Bordeaux, France;(3) Department of Neurosurgery, Bordeaux II University, Bordeaux, France;(4) Department of Pediatry, Bordeaux II University, Bordeaux, France |
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| Abstract: | In a large series of 116 cortical resections for treatment of medically intractable epilepsy, 10 glial hamartomas and 11 neuronoglial malformative lesions were found. Glial hamartomas were astrocytic in 3 cases, oligodendrocytic in 6 and mixed oligoastrocytic in 1. Neuronoglial lesions corresponded to  focal cortical dysplasia in 6 patients and to microdysgenesis in 5 others. This study focuses on the various neuropathological presentations of these malformative epileptogenic lesions, and on correlations with neuro-imaging data. |
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| Keywords: | Hamartoma Focal cortical dysplasia Microdysgenesis Epilepsy |
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