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A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin
Authors:Lisa M. Rice  Julio C. Mantero  Giuseppina Stifano  Jessica Ziemek  Robert W. Simms  Jessica Gordon  Robyn Domsic  Robert Lafyatis
Affiliation:1. Boston University School of Medicine, Boston, Massachusetts, USA;2. Hospital for Special Surgery, New York, New York, USA;3. University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Abstract:
Keywords:dcSSC  diffuse cutaneous systemic sclerosis  ILD  interstitial lung disease  LASSO  least absolute shrinkage and selection operator  MRSS  modified Rodnan skin score  PBMC  peripheral blood mononuclear cell  SSc  systemic sclerosis  TGF  transforming growth factor  TLR  toll-like receptor  TNF  tumor necrosis factor
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