| ~(99m)Tc-MIBI肺亲肿瘤显像与肿瘤标志物联合诊断肺部结节良恶性的临床价值 |
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| 引用本文： | 刘超,马世兴,朱家伦,刘鹏杰,贾莉,王永斌.~(99m)Tc-MIBI肺亲肿瘤显像与肿瘤标志物联合诊断肺部结节良恶性的临床价值[J].临床医学,2010,30(10). |
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| 作者姓名： | 刘超 马世兴 朱家伦 刘鹏杰 贾莉 王永斌 |
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| 作者单位： | 昆明医学院第三附属医院,云南省肿瘤医院核医学科,昆明,650118 |
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| 摘 要： | 目的探讨99mTc-MIBI肺亲肿瘤显像与肿瘤标志物联合诊断肺部结节良、恶性的临床价值。方法对54例CT发现肺部结节的患者行99mTc-MIBI肺亲肿瘤显像与肿瘤标志物测定(包括NSE、CYFRA21-1,采用放射免疫法测定),分别计算出以上2种方法以及联合应用在诊断肺部结节中的灵敏度、特异性、准确性,通过统计学方法将联合应用后的结果分别与单一方法进行比较分析。结果①两种方法联合使用与单用99mTc-MIBI肺亲肿瘤显像相比,灵敏度、特异性、准确性均提高(P0.05)。②两种方法联合使用与单用肿瘤标志物相比,灵敏度、准确性均提高(P0.05),而特异性比较差异无统计学意义。结论 99mTc-MIBI肺亲肿瘤显像与肿瘤标志物测定两种方法联合使用在肺部结节良、恶性鉴别诊断中的价值要高于单一应用。
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| 关 键 词： | 肿瘤标志物 肺部结节 |
The lung tumor imaging of ~(99m)Tc-MIBI combined with tumor markers in diagnosing pulmonary nodules |
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| LIU Chao,MA Shixing,ZHU Jialun,LIU Pengjie,JIA Li,WANG Yongbin.The lung tumor imaging of ~(99m)Tc-MIBI combined with tumor markers in diagnosing pulmonary nodules[J].Clinical Medicine,2010,30(10). |
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| Authors: | LIU Chao MA Shixing ZHU Jialun LIU Pengjie JIA Li WANG Yongbin |
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| Institution: | LIU Chao,MA Shixing,ZHU Jialun,LIU Pengjie,JIA Li,WANG Yongbin.Department of Nuclear Medicine,the Third Affiliated Hospital of Kunming Medical College,the Tumor Hospital of Yunnan,Kunming 650118,China |
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| Abstract: | Objective To discuss the clinical value of 99mTc-MIBI lung tumor-imaging combined with tumor markers to detect benign and malignant pulmonary nodules.Methods Fifty-four patients who were detected pulmonary nodules by the X-ray computed tomography were researched,and all of them underwent the lung tumor imaging of 99mTc-MIBI,the detection of serum tumor markers(include NSE and CYFRA211,detected by RIA),calculated separately the sensitivity,specificity and accuracy,then combined two methods to diagnose the pu... |
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| Keywords: | 99mTc-MIBI |
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