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槲寄生提取物的抗衰老实验研究
引用本文:李晓斌.槲寄生提取物的抗衰老实验研究[J].云南中医学院学报,2001,24(1):13-14,23.
作者姓名:李晓斌
作者单位:西京医院中医科,
摘    要:目的:观察槲寄生Viscum coloratum Nakai,提取液抗衰老作用。方法:槲寄生提取液按10g/kg,20g/kg给老年大鼠连续灌胃30d后,测血清过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GSH-Px)和下丘脑超氧化物岐化酶(SOD)活性,脑组织丙二醛(MDA)、脑组织和肝脏脂褐质(Lf)含量。结果:槲寄生两剂量组均能明显提高老年大鼠血清CAT、GSH-Px活性,降低老年大鼠脑组织MDA含量、脑和肝组织Lf含量,并可提高老年大鼠下丘脑SOD活性。结论:槲寄生提取液可通过改善自由基代谢而发挥抗衰老作用。

关 键 词:槲寄生  过氧化脂质  抗氧化酶  脂褐质  抗衰老  大鼠  中药提取物
文章编号:1000-2723(2001)01-0013-02

Study on Anti-senility Test With Extract from Ramulus Visci
LI Xiao-bin.Study on Anti-senility Test With Extract from Ramulus Visci[J].Journal of Yunnan College of Traditional Chinese Medicine,2001,24(1):13-14,23.
Authors:LI Xiao-bin
Abstract:In order to observe the anti-senility effect of extract from Ramulus visci,the activity of blood serum CAT,GSH-Px,the activity of hypothalamus SOD,MDA of brain tissue and Lf content of brain tissue and liver have been determined,after old rats have been given the drug(ig),extact from Ramulus visci for 30 days in the light of 10g/kg,20g/kg.which shows the activity of blood serum CAT,GSH-PX,and hypothalamus SOD in old rats in the two groups can be obviously increased.It can also decrease content of MDA of brain tissue and liver.It is concluded that extract from Ramulus visci play the effect of anti-senility through improving free radical.
Keywords:Chinese materia medica  Ramulus visci  Peroxide  Lipofuscin  Antioxidase  Anti-senility
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