单侧多囊卵巢临床特征的对比性研究

目的通过对单侧多囊卵巢(PCO)临床特征的对比分析,探讨其与多囊卵巢综合征(PCOS)的关系。方法选择单侧PCO 32例,PCOS组40例及对照组26例为研究对象,对其临床特征、内分泌及代谢指标进行比较分析。结果PCO组与PCOS组及对照组在痤疮、多毛及体重指数差异无统计学意义,而月经失调差异有统计学意义。PCO组的LH、LH/FSH>2、T明显低于PCOS组;LH/FSH>2在PCO组显著低于对照组;餐后2小时胰岛素和胰岛素抵抗指数在PCO组与PCOS组及对照组比较差异有显著统计学意义(分别为P<0.01,P<0.05)。结论PCO患者存在一定程度内分泌及代谢方面的变化,它可能是正常人群向PCOS转变的一种过渡状态,是否进行临床干预有待于研究。

Comparison of clinical characterization in unilateral polycystic ovary

Objective To investigate relationship between unilateral polycystic ovary and polycystic ovary syndrome by comparing the clinical characterization.MethodsEndocrine and metabolic parameters were measured in three groups(unilateral polycystic ovary(PCO,n=32),polycystic ovary syndrome(PCOS,n=40) and control group,n=26).ResultsThere were no significant difference in acne,hirsutism and body mass index,and menstrual disturbance showed significantly among three groups;LH,LH/FSH>2,T in unilateral PCO group were significantly lower,compared with PCOS group;The cases of LH/FSH >2 in unilateral PCO group were lower than that in control group;The unilateral PCO group showed significant difference in serum insulin(2-hours after take oral glucose load) and IR compared with other group(P<0.01,P<0.05).ConclusionThe patients of unilateral PCO present endocrine and metabolic changes,which might be the transition status from normal to PCOS.