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| 职业接触抗癌药物的诱变效应 | |
| 引用本文： | 陈少华. 职业接触抗癌药物的诱变效应[J]. 职业卫生与病伤, 1994, 9(3): 138-140 |
| 作者姓名： | 陈少华 |
| 作者单位： | 空军福州医院遗传学研究室 |
| 摘 要： | 对１５名长期接触抗癌药物的护士进行外周血淋巴细胞微核率和姊妹染色单体交换（ＳＣＥ）率检测，结果表明，她们的微核率很显著高于献血员（Ｐ＜０．０１）；其ＳＣＥ率亦高于献血员，差异显著（Ｐ＜０．０５）。作者呼吁职业接触抗癌药物者应重视自身防护，严格操作规程，将污染危害降到最低限度。 |
| 关 键 词： | 抗癌药物，微核，姊妹染色单体交换 |
THE MUTAGENESITY EFFECT OF PROFECTIONALLY GETTING IN TOUCH WITH ANTICANCER DRUGS |
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| Chen shaohua. THE MUTAGENESITY EFFECT OF PROFECTIONALLY GETTING IN TOUCH WITH ANTICANCER DRUGS[J]. Journal of Occupational Health and Damage, 1994, 9(3): 138-140 | |
| Authors: | Chen shaohua |
| Affiliation: | Genetics Laboratory of Air Force Fuzhou Hospital 350002 |
| Abstract: | he frequencies of micronucleus and sister chromatid exchange(SCE)in peripheral lym-phocytes of 15 cases nurses professionally coming into contact with anticaricer drugs havebeen examined, the result shows that the micronucleus frequency of the nurses is greatlyhigher than the blood donors(P<0.01),and the SCE frequency of the former is higher thanthe later,too(P<0.05).We appeal for that the persons who professionally come into contactwith themotherapy medicines shoud pay attention to protect themselves,operate to be stan-dardized ,lower the hazard of the pollution to the limit. |
| Keywords: | Anticancer drugs Micronucleus Sister chromated exchange(SCE) |
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