| 原发性肺大B细胞淋巴瘤的临床病理研究 |
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| 引用本文： | 段立,潘铁成,魏翔,刘立刚,胡敏,徐利军.原发性肺大B细胞淋巴瘤的临床病理研究[J].临床肺科杂志,2009,14(8):1004-1005. |
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| 作者姓名： | 段立 潘铁成 魏翔 刘立刚 胡敏 徐利军 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院心胸外科,武汉,430030 |
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| 摘 要： | 目的探讨原发性肺弥漫性大B细胞淋巴瘤的组织学特点和免疫表形特征。方法运用组织形态学和免疫组织化学方法研究我院1例肺弥漫性大B细胞淋巴瘤患者的临床表现、病理特点和免疫组化标记特点。结果肉眼观察肿瘤为灰白色不规则分叶状团块，切面灰白色，鱼肉样，有大量坏死灶；显微镜观察被覆呼吸上皮下中心母细胞样细胞弥漫增生，浸润肺组织，瘤细胞坏死明显。免疫组化：CD20（＋），CD79α（＋），CD3（-），CD45RO（-），PCK（-）。结论弥漫性大B细胞淋巴瘤是一种少见的恶性肿瘤，而原发于肺的DLBCL更极为罕见。该病缺乏典型的临床表现，极易误诊。肺弥漫性大B细胞淋巴瘤的诊断和鉴别诊断，要以组织病理学形态为基础并与免疫组织化学相结合。
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| 关 键 词： | 肺 弥漫性大B细胞淋巴瘤 结外淋巴瘤 病理 免疫组化 |
Pathologic character and diagnosis of primary lung diffuse large B cell lymphoma |
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| DUAN Li,PAN Tie-cheng,LIU Li-gang,XU Li-jun,WEI Xiang,HU Min.Pathologic character and diagnosis of primary lung diffuse large B cell lymphoma[J].Journal of Clinical Pulmonary Medicine,2009,14(8):1004-1005. |
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| Authors: | DUAN Li PAN Tie-cheng LIU Li-gang XU Li-jun WEI Xiang HU Min |
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| Institution: | DUAN Li,PAN Tie-cheng,LIU Li-gang,XU Li-jun,WEI Xiang,HU Min Department of Cardiac , Thoracic Surgery,Tongji Hospital Affiliated to Tongji Medical College,Huazhong University of Science , Technology,Wuhan City,Hubei Province,Wuhan 430030,China |
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| Abstract: | Objective To study the pathologic character and diagnosis of primary lung diffuse large B cell lymphoma. Methods The study analyzed the clinical manifestations,pathologic character and immunohistochemical character of one lung diffuse B cell lymphoma patent. Results In visual observation,it's a gray irregular lobulated mass,section was gray,fish-like,and number of necrotic foci. Observed under the microscope,we found subepithelial respiratory center oocyte-like cells diffuse proliferative,infiltration in lu... |
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| Keywords: | lung diffuse large B cell lymphoma extranodal lymphoma pathology immunohistochemistry |
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