| 房间隔缺损介入治疗后右房室重构研究 |
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| 引用本文： | 王洪,洪浪,陆林祥,陈章强,胡耀.房间隔缺损介入治疗后右房室重构研究[J].江西医药,2011,46(8):689-691. |
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| 作者姓名： | 王洪 洪浪 陆林祥 陈章强 胡耀 |
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| 作者单位： | 江西省人民医院心内二科,南昌,330006 |
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| 摘 要： | 目的评价卡托普利及氯沙坦逆转房间隔缺损（ASD）封堵术后右房右室重构,改善心脏功能的临床疗效。方法 90例成功进行了封堵治疗的ASD患者,男40例,女50例;年龄14-78岁（32.12±10.83）岁。随机分为卡托普利组、氯沙坦组和对照组。术前、术后3d及术后6个月行超声心动图检查（TTE）,观察右房室重构数据。结果与术前相比3组右房、右室内径及右室舒张末期容积均有减小,左室内径增大,左右心比例趋于正常;卡托普利组与氯沙坦组右房右室改变均较对照组有明显不同,具有统计学意义（P〈0.05）,而两组间改变无统计学意义（P〉0.05）。结论卡托普利和氯沙坦均有助于逆转ASD所致的心脏病理变化,逆转右房右室重构,改善心功能。
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| 关 键 词： | 房间隔缺损 封堵术 卡托普利 氯沙坦 右房右室重构 |
The study of the right atrium and the right ventricle remodeling after transcatheter closure of atrial septal defect |
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| Wang Hong,Hong Lang,Lu Linxiang,et al..The study of the right atrium and the right ventricle remodeling after transcatheter closure of atrial septal defect[J].Jiangxi Medical Journal,2011,46(8):689-691. |
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| Authors: | Wang Hong Hong Lang Lu Linxiang |
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| Institution: | Wang Hong,Hong Lang,Lu Linxiang,et al.the second department of cardiology,Jiangxi province people's hospital,Nanchang,330006,China |
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| Abstract: | Objective To evaluate the clinical efficacy of Captopril and Losartan to reverse right atrium and right ventricle re-modeling after transcatheter closure of atrial septal defect.Methods Ninety patients after transcatheter closure of atrial septal defect were divided into 3 groups:Captopril group,Losartan group and control group.Ehocardiography examinations was performed before and 6 month after closure of ASD,To observe right atrium and right ventricular remodeling data.Results Comparing with captopril grou... |
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| Keywords: | atrial septal defect transcat heter closure Captopril Losartan right atrium and right ventricular remodeling |
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