氟比洛芬酯对大容量肺灌洗患者全麻苏醒期躁动的影响

目的：探讨氟比洛芬酯对大容量肺灌洗患者全麻苏醒期躁动的影响。方法选择本院2012年4月～2012年11月间进行肺灌洗的患者220例,随机分为观察组和对照组,各110例,停麻醉药前30 min,观察组静脉注射氟比洛芬酯50 mg（缓慢静脉注射2 min）,对照组静脉注射生理盐水5 ml,拔管10 min后观察躁动发生率和身体舒适度。结果观察组患者躁动发生率明显低于对照组,观察组身体舒适度评分明显高于对照组,差异均有统计学意义（P〈0.05）。结论氟比洛芬酯对大容量肺灌洗患者全麻苏醒期躁动的发生有预防和减少的作用。

Effect of flurbiprofen axetil on whole-lung lavage agitation in patients during anesthesia recovery period

Objective To investigate the effect of flurbiprofen axetil on large volume lung lavage agitation in patients during anesthesia recovery period. Methods 220 cases of lung lavage patients in our hospital from April 2012 to November 2012, were randomly divided into observation group and control group, each 110 cases. 50mg flurbiprofen （intravenous injection slowly for 2 minutes） for the observation group and 5ml saline intravenous injection for the control group, are executed 30 minutes before stopping anaesthetic drugs. Observe the incidence of agitation and physical comfort 10 minutes after extubation. Results The incidence was significantly lower than the control group. Physical comfort evaluation in observation group was significantly higher than the control group. And the difference was statistically significant （P＆lt;0.05）. Conclusion Flurbiprofen axetil can prevent and reduce agitation for the patients of large volume lung lavage during recovery period of general anesthesia.