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Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase
Authors:Katerina Machova Polakova  Vojtech Kulvait  Adela Benesova  Jana Linhartova  Hana Klamova  Monika Jaruskova  Caterina de Benedittis  Torsten Haferlach  Michele Baccarani  Giovanni Martinelli  Tomas Stopka  Thomas Ernst  Andreas Hochhaus  Alexander Kohlmann  Simona Soverini
Affiliation:1. Institute of Hematology and Blood Transfusion, Prague, Czech Republic
2. First Faculty of Medicine, Institute of Clinical and Experimental Hematology, Charles University, Prague, Czech Republic
3. PersMed, Dolni Brezany, Czech Republic
4. First Faculty of Medicine, Institute of Pathologic Physiology, Charles University, Prague, Czech Republic
5. Department of Experimental, Diagnostic and Specialty Medicine, Institute of Hematology “L. e A. Seràgnoli”, University of Bologna, Bologna, Italy
6. MLL Munich Leukemia Laboratory, Munich, Germany
7. Abteilung für H?matologie/Onkologie, Klinik für Innere Medizin II, Universit?tsklinikum Jena, Jena, Germany
8. AstraZeneca, Personalized Healthcare and Biomarkers, Innovative Medicines, Cambridge, UK
Abstract:
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