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Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities
Authors:Judith Niesen  Christoph Stein  Hannes Brehm  Grit Hehmann-Titt  Rolf Fendel  Georg Melmer  Rainer Fischer  Stefan Barth
Affiliation:1. Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Forckenbeckstrasse 6, 52074, Aachen, Germany
2. Department of Experimental Medicine and Immunotherapy, Institute of Applied Medical Engineering, RWTH Aachen University Clinic, Aachen, Germany
4. Pharmedartis GmbH, Aachen, Germany
3. Institute of Molecular Biotechnology (Biology VII), RWTH Aachen University, Aachen, Germany
Abstract:
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