| 含草酸铂方案治疗晚期贲门癌的疗效观察 |
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| 引用本文： | 马保庆,张春珍,张中祥,.含草酸铂方案治疗晚期贲门癌的疗效观察[J].中国医学工程,2006,14(5):521-522. |
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| 作者姓名： | 马保庆 张春珍 张中祥 |
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| 作者单位： | 1. 河南省安阳市肿瘤医院,内科,河南,安阳,455000
2. 河南省卫生学校附属医院,普外科,河南,安阳,455000 |
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| 摘 要： | 目的观察草酸铂(L-OHP)联合5-氟脲嘧啶(5-Fu)、亚叶酸钙(CF)治疗晚期贲门癌的疗效与毒性。方法L-OPH135mg/m2ivgttD1,5-Fu350mg/m2ivgttD2-6,CF100mg/m2D2-6,21d为1周期。结果全组患者获得CR4例,PR12例,NC10例,PD4例,总有效率(CR+PR)为53.3%;骨髓抑制和胃肠道反应均为0-II°,80%患者出现外周感觉神经异常。结论该方案治疗晚期贲门癌疗效高,副作用少,值得临床应用。
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| 关 键 词： | 草酸铂 亚叶酸钙 5-氟脲嘧啶 晚期贲门癌 化疗 |
| 文章编号： | 1672-2019（2006）05-0521-02 |
| 收稿时间： | 2006-03-01 |
| 修稿时间： | 2006年3月1日 |
Clinical observation of chemical therapeutic regimen including oxaliplatin in treatment of advanced cardiac cardiac carcinoma |
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| MA Bao-qing,ZHANG Chun-zhen,ZHANG Zhong-xiang.Clinical observation of chemical therapeutic regimen including oxaliplatin in treatment of advanced cardiac cardiac carcinoma[J].China Medical Engineering,2006,14(5):521-522. |
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| Authors: | MA Bao-qing ZHANG Chun-zhen ZHANG Zhong-xiang |
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| Abstract: | Objective] To evaluate the efficacy and safety of OXA-LV/5-FU regimen for patients with advanced cardiac carcinoma.Methods] Patients with advanced cardiac carcinoma were treated with 135 mg/m2 iv d1,5-Fu 350 mg/m2 iv d2-6 and CF 100 mg/m2 iv d2-6 in 21days per cycle.Results] Thirty patients had enrolled our study.4,12,10 and 4 patients achieved CR,PR,NC and PD respectively.Overall response rate(CR+PR)for chemotherapy was 53.3%.Myelosuppression and digestive tract toxity were 0-II degree but 80% patients had the complication of peripheral nerve paresthesia.Conclusion] Due to good efficacy and tolerability,this regimen offers a good candidate for treating advanced cardiac carcinoma |
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| Keywords: | oxaliplatin calcium folinate 5-flurouracil advanced cardiac carcinoma chemical therapy |
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