Coproverdine,a novel,cytotoxic marine alkaloid from a new zealand ascidian |
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Authors: | Urban Sylvia Blunt John W Munro Murray H G |
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Affiliation: | Department of Chemistry, University of Canterbury, Private Bag 4800, Christchurch, New Zealand. |
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Abstract: | The crude extract of a New Zealand ascidian displayed antitumor activity. Bioassay-directed fractionation yielded a novel alkaloid, coproverdine (1). The structure of 1 was assigned on the basis of detailed spectroscopic analysis. Coproverdine (1) was responsible for the antitumor activity of the crude extract. |
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