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黄葵胶囊对慢性盆腔炎的临床干预研究
引用本文:张申华,杨艳华. 黄葵胶囊对慢性盆腔炎的临床干预研究[J]. 职业与健康, 2013, 0(21): 2889-2890
作者姓名:张申华  杨艳华
作者单位:湖北省天门市第一人民医院妇产科,433000
摘    要:
目的观察黄葵胶囊对慢性盆腔炎的临床疗效,并探讨其可能机制。方法共计124例慢性盆腔炎患者纳入研究,并随机分为两组:对照组(n=58)与干预组(n=66)。所有患者均给予抗炎、营养支持等常规治疗。干预组在上述治疗的基础上加用黄葵胶囊治疗。记录两组症状体征、血清炎症因子、氧化应激指标。结果对照组总有效率为93.1%,干预组总有效率为92.4%,总有效率差异无统计学意义(P〉0.01),但后者显效率更高(P〈0.01)。经过治疗后,两组患者血清炎症因子与氧化应激水平均下降(P〈0.01),干预组更为明显(P〈0.01)。结论黄葵胶囊对慢性盆腔炎有较好的临床干预作用,可提高治疗后的显效率,降低体内的炎症与氧化应激水平。

关 键 词:黄葵胶囊  慢性盆腔炎  炎症  氧化应激

Study on clinical efficacy of Huangkui Capsule on chronic pelvic inflammatory disease
ZHANG Shen-hua,YANG Yan-hua. Study on clinical efficacy of Huangkui Capsule on chronic pelvic inflammatory disease[J]. Occupation and Health, 2013, 0(21): 2889-2890
Authors:ZHANG Shen-hua  YANG Yan-hua
Affiliation:Department of Gynaeeology and Obstetrics, the First People Hospital of Tianmen City, Hubei, 433000, China
Abstract:
[ Objective] To observe the clinical efficacy of Huangkui Capsule on chronic pelvic inflammatory disease (CPID) , explore its mechanism. [ Methods] 124 CPID patients were randomly divided into the control group (58 cases) and the intervention group ( 66 cases ). All patients received the conventional treatments of anti-inflammatory and nutritional support, and the interven- tion group was given Huangkui Capsule on this basis. The signs and symptoms, levels of serum inflammatory cytokines and oxida- tive stress parameters were recorded in two groups. [ Results ] The total effective rate of the control group and the intervention group was 93.1% and 92.4% respectively, and there was no significant difference ( P 〉0.01 ) , but the obvious effective rate of the in- tervention group was higher than that of the control group ( P 〈 0. 01 ). The levels of serum inflammatory cytokines and oxidative stress in both two groups reduced after treatment ( P 〈 0.01 ) , while the decreases were more obvious in the intervention group (P 〈0.01). [Condusion] Huangkui Capsule has good clinical curative effect on CPID, which can improve the obvious effective rate, and decrease the levels of serum inflammatory cytokines and oxidative stress.
Keywords:Huangkui Capsule  chronic pelvic inflammatory disease ( CPID )  Inflammation  Oxidative stress
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