幽门螺杆菌感染与慢性肝病的研究进展

幽门螺杆菌(HP)是一种微需氧革兰阴性杆菌。目前对于HP的致病性研究主要集中在胃肠相关疾病的领域,如慢性胃炎、消化性溃疡、胃癌以及胃淋巴瘤等。近年来的研究已证实在慢性肝、胆疾病及肝癌患者的肝组织中检测到HP的存在,提示HP可能是导致肝脏病变独立的或辅助的致病因素。现主要对HP感染与慢性肝病及其并发症方面的研究进展予以综述。

Research Progress of Helicobacter pylori and Chronic Liver Disease

Helicobacter pylori(HP)is a Gram′s negative spiral bacterium.Recently,the study of HP pathogenicity focuses mainly on the gastrointestinal diseases,such as chronic gastritis,peptic ulcer,gastric cancer,gastric lymphoma and so on.It has proved that the existence of HP in chronic hepatitis,gallbladder disease and hepatocellular carcinoma,suggesting that HP may be the independent cause of liver diseases or auxiliary pathogenic factors.The research progress of HP infection in chronic liver disease and the complications are reviewed in this article.