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Chromosome studies in a case of monoblastic leukemia
Authors:S.W. Soukup  J.E. Neely
Affiliation:1. Children''s Hospital Research Foundation, Division of Teratology and Genetics, Cincinnati, Ohio USA;2. Children''s Hospital Research Foundation, Division of Hematology and Oncology, Cincinnati, Ohio USA
Abstract:
Chromosome analysis of a direct bone marrow preparation from a patient with acute, undifferentiated monoblastic leukemia showed a predominant clone of 51,XX,+6,+8,+14,+19,+21,11q+, along with a chromosomally normal clone. Studies with cytofluorometry confirmed the two populations of cells with different DNA content.
Keywords:Address requests for reprints to: Dr. Shirley Soukup   Children's Hospital Research Foundation   Elland and Bethesda Avenues   Cincinnati   Ohio 45229 USA.
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