老年患者股动脉粥样硬化与冠心病关系的研究

目的研究老年患者股动脉粥样硬化与冠心病的关系。方法110例老年患者按冠状动脉造影的结果分成对照组(32例)及冠心病组(78例),冠心病组根据冠状动脉病变支数又分3个亚组:分别为1支病变组,16例;2支病变组,34例;3支病变组,28例。均行双侧股动脉超声检查,测量股动脉后壁内膜中层厚度(IMT),斑块厚度及粥样斑块发生率,并与冠状动脉造影结果进行对比分析。结果冠心病组IMT、斑块积分及斑块发生率明显高于对照组,差异有显著性意义(P<0.01);随冠状动脉病变支数增加,斑块积分及IMT也增加,各组比较差异有显著性意义(P<0.01);以IMT>0.85 mm和(或)出现粥样斑块预测冠心病,特异性75.0%,敏感性87.1%,阳性预测率89.3%。结论老年患者股动脉粥样硬化严重程度与冠心病发生率成正比;通过股动脉超声检查可为冠心病的诊断提供依据。

Is femoral atherosclerosis closely associated with coronary heart disease in elderly patients?

Objective To investigate the relationship between femoral artery atherosclerosis and coronary heart disease(CHD) in elderly patients.Methods A total of 110 patients were divided into control group and CHD group according to the results of coronary angiography.In CHD group there were three subgroups according to its involved branch numbers,i.e.,one involved branch subgroup(16 cases),two involved branch subgroup(34 cases) and three involved branch subgroup(28 cases).All patients were investigated by double femoral artery ultrasonic examination.The femoral intima-media wall thickness(IMT),crouse score and plaque incidence were measured.Results The IMT,crouse score and plaque incidence were significantly higher in CHD groups than in controls.A linear correlation between the IMT,crouse score and the extent of CHD was found.The specificity and sensitivity of using IMT>0.85 mm and/or femoral atherosclerosis plaque with diagnosis CHD were respectively 75.0%,87.1%,the positive predictability was 89.3%.Conclusion CHD in elderly patients is associated with a higher incidence of and more extensive arteriosclerosis in femoral artery;femoral ultrasound examination can provide useful information in the diagnosis of CHD.