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| 冠心康颗粒质量标准研究 | |
| 引用本文： | 张晓明,何晓英. 冠心康颗粒质量标准研究[J]. 中国药事, 2010, 24(4): 380-382 |
| 作者姓名： | 张晓明 何晓英 |
| 作者单位： | 甘肃省药品检验所,兰州,730000 |
| 摘 要： | 目的制定冠心康颗粒质量标准。方法用TLC法进行定性鉴别,以RP-HPLC测定丹酚酸B的含量。采用C18柱,流动相为乙腈-甲醇-甲酸-水（10∶30∶1∶59）,检测波长为286nm。结果TLC可以鉴别赤芍、川芎、红花,丹酚酸B的线性范围为0.146-1.75mg,平均回收率为98.0%。结论定性、定量方法简便、可靠、准确,可用于冠心康颗粒的质量标准。 |
| 关 键 词： | 冠心康颗粒 TLC HPLC 质量标准 |
Study on Quality Standard for Guanxinkang Granules |
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| Zhang Xiaoming , He Xiaoying. Study on Quality Standard for Guanxinkang Granules[J]. Chinese Pharmaceutical Affairs, 2010, 24(4): 380-382 | |
| Authors: | Zhang Xiaoming He Xiaoying |
| Affiliation: | Zhang Xiaoming , He Xiaoying(Gansu Provincial Institute for Drug Control,Lanzhou 730000) |
| Abstract: | Objective To estabolish the method for quality control of Guanxinkang Granules.Methods Using TLC to identify the granules.Salvianolic acid B in granules was determined by RP-HPLC.Using C18 column,the mobile phase was made from acetonitrile-methanol-methanoic acid-water（10∶30∶1∶59）;the detection wavelength was at 286nm.Results The herbs could be identified by TLC.For Salvianolic acid B,the linear range was from 0.146~1.75mg,and the average recovery was 98.0%.Conclusion The method is simple,reliable and accurate.It can be applied to the quality control of Guanxinkang Granules. |
| Keywords: | TLC HPLC |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |