老年患者常见假单胞菌感染及其药敏分析

目的探讨老年患者对临床常见假单胞菌感染的特点、分布和耐药谱,对多重耐药性状况进行分析,为指导临床合理用药提供依据。方法用微生物分析仪,并结合传统手工非发酵微量生化管编码补充试验进行菌种鉴定;药敏试验采用K—B琼脂纸片扩散法及法国梅里埃ATB试条。结果共分离出286株假单胞菌,以铜绿假单胞菌居多,有201株占70．3％,其次是的氏不动杆菌、嗜麦芽假单胞菌,分别有37株和 22株占12．9％、7．7％。呼吸系统标本有229株占分离株的80．0％。铜绿假单胞菌、鲍氏不动杆菌对阿米卡星 (AKN)、亚胺培南(1MP)、多粘菌素E(COL)抗菌活性高,嗜麦芽假单胞菌对复方新诺明(TSU)抗菌活性高。结论老年患者对临床常见假单胞菌感染率高,耐药谱多为多重耐药性,患者年龄越大检出率及多重耐药率越高。

COMMON PSEUDOMONAS INFECTION OF SENILE PATIENTS AND ITS DRUG SENSITIVITY ANALYSIS

Objective Probe into the characteristics, distribution and drug-resistant spectrum of commonpseu-domonas infection of senile patients, and analyze the status of multiple drug-resistant in order to guide reasonable use of drug in clinic. Method To identify the bacterial species with microbiological assay instrument combined traditional manual non-fermentative microbiological tube coding; detect the drug sensitivity with K-B agar tape diffusion and French MEILIE ATB test tape. Result 286 strains of pseudomonas were isolated, most of which were pseudomonas aeruginosa account for 201, 70.3%; in the next place were Bao' s amotile bacillus and maltobiosephilia pseudomonas account for 37, 22 strains, 12.9%, 7.7% respectively. There were 229 strains from respiratory tract account for 80.0% of isolates. Pseudomonas aeruginosa and Bao's amotile bacillus have high sensitiveness to Amikacin, Imipenem, Polymyxin E; maltobiosephilia pseudomonas has high sensitiveness to Sulfamethoxazole Compound. Conclusion Senile patients have high infection rate to common pseudomonas, its drug-resistant usually were multiple drug-resistant, the higher patient's age the higher rate of isolating and drug-resistant.