| Abstract: | The incidence of sickle cell trait varies among blacks in North America. Although the average hemoglobin (Hb)-AS gene frequency is 8% in the United States, a value of 13.4% was recorded in South Carolina. Preliminary studies during a two-day community sponsored health fair in Selma, Alabama, revealed a sickle cell gene frequency of 15.96%. This study also found an intermediate frequency of 12.4% in a family practice center that is accredited for a residency program. Through a screening program, sickle cell trait was detected, a rigorous training program for resident physicians in family practice was implemented, and proper counseling to patients with hemoglobinopathies was provided. In the authors' judgment, laboratory screening for sickle cell trait is a first step toward genetic counseling and medical practice by family physicians and general practitioners. |
