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| 大Y染色体对体外受精-胚胎移植妊娠结局的影响 | |
| 引用本文： | 刘春莲,哈灵侠,景万红,吴昕,胡蓉,赵君利,焦海燕,徐仙. 大Y染色体对体外受精-胚胎移植妊娠结局的影响[J]. 宁夏医学杂志, 2011, 33(9): 811-813 |
| 作者姓名： | 刘春莲 哈灵侠 景万红 吴昕 胡蓉 赵君利 焦海燕 徐仙 |
| 作者单位： | 1. 宁夏医科大学附属医院,宁夏,银川,750004 2. 宁夏医科大学,宁夏,银川,750004 |
| 基金项目： | 宁夏医科大学面上科研项目 |
| 摘 要： | 目的探讨在人类辅助生殖技术中大Y染色体对精液常规、胚胎发育及妊娠结局的影响。方法对进行体外受精/单精子显微卵胞浆内注射-胚胎移植（IVF/ICSI-ET）助孕的410例患者（共423个周期治疗）进行前瞻性研究,筛选出大Y染色体组共20个治疗周期,染色体正常组30个周期,对其精液常规和形态及助孕的各个环节指标进行归纳分析。结果①组间精液常规比较,大Y组精液密度,a、b级,活率及形态低于对照组,但差异无统计学意义（P〉0.05）;②组间一般资料的比较,男、女方患者的平均年龄、不孕年限、获卵数、移植胚胎数比较,差异均无统计学意义（P〉0.05）;③组间胚胎发育参数的比较,大Y组受精率（77.15%）显著低于对照组（88.20%）,而卵裂率、优质胚胎形成率显著高于对照组,差异均有统计学意义（P〈0.05）;④两组间妊娠结局的比较,临床妊娠率、种植率、流产率、异位妊娠率、死婴出生率、畸形率,差异均无统计学意义（P〉0.05）。结论大Y染色体对精液常规和临床妊娠结局无明显影响。 |
| 关 键 词： | 大Y染色体 精液常规 胚胎发育 妊娠结局 |
Influence of big Y chromosome on in vitro fertilization and embryo transfer |
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| LIU Chun-lian,et al.. Influence of big Y chromosome on in vitro fertilization and embryo transfer[J]. Ningxia Medical Journal, 2011, 33(9): 811-813 | |
| Authors: | LIU Chun-lian et al. |
| Affiliation: | LIU Chun-lian,et al.(The Affiliated Hospital of Ningxia Medical University,Yinchuan 750004,China) |
| Abstract: | Objective To explore the influence of big Y chromosome on the semen parameter and outcome of in vitro fertilization and embryo transfer.Methods The data from 410 infertile patients who underwent IVF /ICSI-ET of total 423 cycles of the treatment were studied.20 treatment cycles were performed on the big Y chromosome group and 30 cycles on the normal karyotype group.Results There was no significant difference in the fertilization rate,cleavage rate,quality of transferred embryos,clinical pregnancy rate,implan... |
| Keywords: | Y chromosome karyotype Semen parameter Embryo development Pregnancy outcome |
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